Pepe Serna is an American film and television actor and artist. Serna's first break in movies came in 1970 on the Roger Corman directed film The Student Nurses. Over the years Serna has appeared in over 100 films.
Serna has been honored by the Screen Actors Guild Heritage Achievement Award; the League of United Latin American Citizens, and the Estrella Award for Arts & Culture from the Orange County Hispanic Chamber of Commerce. Pepe played Señor Cárdenas in the movie Downsizing.